Correlates of Psychosis in AD

 
   Lead Investigator:    Robert Sweet
   Institution      :    University of Pittsburgh
   E-Mail           :    sweetra@upmc.edu
   Proposal ID      :    63


   Publications:


1  Demichele-Sweet MA, Lopez OL, Sweet RA
   Psychosis in Alzheimer's disease in the national Alzheimer's disease coordinating center uniform data set: clinical correlates and association with apolipoprotein e
   Journal Article  Int J Alzheimers Dis,2011:926597,2011,PMC3065057

   PUBLISHED





   Proposal Description:
   To better characterize the AD+P syndrome for future genetic and neurobiologic  studies, we now propose to utilize the UDS data set to definitively  characterize the clinical correlates of AD+P, and the extent to which APOE  genotype contributes to AD+P risk.   1. To determine the clinical correlates of psychosis in AD. We hypothesize that  psychosis is associated with greater cognitive impairment.   2. To determine whether APOE genotype is associated with psychosis in AD. We  hypothesize that APOE genotype is not associated with psychosis in AD.